Hydroxyapatite (HAp) for a wide range of applications in the biomedical field

Hydroxyapatite (HAp) is the major component, and an essential ingredient, of normal bone and teeth. The synthetic and natural HA differ in terms of physical microstructure, crystal size, and porosity, but chemical similarities to bone, in both forms, as well as biocompatibility, bioactivity and thermal stability in the body fluid pose Hydroxyapatite (HAp)  as an attractive material for a wide range of applications in the biomedical field. HAp is widely used as an implant for bone tissue regeneration, as a coating for metallic implants and in drug-controlled release. The osseointegration of an implant can be accelerated by a hydroxyapatite coating.

The ingrowth process time of the HA-coated prosthesis is identical to the healing process of a bone fracture. Due to their exceptional properties, nanopowders and mesoporous HA can be bonded directly to bone and may stimulate the implant integration. Among the tissue engineers, HAp remains the first material of choice for bone tissue engineering. HA nanocrystals/particles have been used for the surface modification of dental implants.

Hydroxyapatite (HA) can be synthesized by several methods, for obtaining various forms which may be used in several applications.
Several efforts have been focused on the synthesis of particles of this material aiming to the precise control of size and morphology, porosity, and surface area.

  • Density
  • Surface area
  • Porosity
  • Particle size and shape
  • High resolution SEM images
  • Thermal analysis
  • Powder flow properties

Alfatestlab is equipped with all these analytical techniques necessary to support you. Contact us to discuss your analytical needs!




Cerâmica vol.65 no.374 São Paulo Apr./June 2019 Epub June 06, 2019

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