Automatic Image Analysis
Static Automated Image Analysis is the ideal technique to obtain, through high quality images on statistically representative numbers of particles, accurate information about particle shape (circularity, elongation, convexity, etc.), particle size and particle transparency. The reproducibility of the measurements obtained with the instrument installed in Alfatestlab is also guaranteed by an automated particle dispersion system. The technique is validated by the ISO13322-1: 2014.
We can perform automatic measurements on filters to quantify and differentiate the presence of contaminants or oversized particles, useful information for industries such as pharmaceutical, automotive, environmental, etc.
Thank to Morphologically Directed Raman Spectroscopy MDRS integrated in the Morphologi 4ID system Alfatestlab can provide Raman spectra of any particle in order to chemically identify it in a multi-component sample. Ask us more about it!
Scanning Electron Microscopy
Scanning Electron Microscopy (SEM) is used in many areas not strictly related to particles. For particle size and particle shape analysis, the SEM present in Alfatestlab is coupled to an automatic powder dispersion system on the stubs and to a dedicated software called ParticleMetric able to provide automatic reports on particle size distribution and particle shape.
Analysis of coffee particle characteristics, coffee creaming and bulk powder flow properties together with sensory analysis and high resolution SEM images can help you improve your coffee production process.
The unique potential of graphene, offering the theoretical strength of diamond together with the flexibility of plastic, finds application in a wide range of industries: from electronics to drug delivery. Graphene quality varies considerably depending on how the material is produced, so characterizing raw material and finished products is of fundamental importance.
Zinc oxide (ZnO) is an inorganic white powder, insoluble in water and used as an additive in numerous materials and products. Characterization of Zinc oxide powder and particles properties is fundamental to improve final product quality.
Chocolate is a complex suspension of non-fat particles (sugar, cocoa, milk powder particles) dispersed in cocoa butter. Particle size, rheology and thermal analysis help controlling texture, flavour and stability propeties of chocolate products. Discover how...
Today let's focus on dissolution, and on the reasons why this property of food materials is so important to characterize...
The synthetic and natural HA differ in terms of physical microstructure, crystal size, and porosity, but chemical similarities to bone, in both forms, as well as biocompatibility, bioactivity and thermal stability in the body fluid pose Hydroxyapatite (HAp) as an attractive material for a wide range of applications in the biomedical field. Find out more!
Physical properties of excipients influence the stability, bioavailability, and processability of the dosage forms. Alfatestlab is equipped with all the analytical techniques necessary to support you in choosing the right excipient for your formulation: particle size, particle shape, flowability, density, surface area and much more!
Silica is one of the most complex and most abundant families of materials: sand, quartz, silica gels, precipitated silica, fumed silica, colloidal silica, mesoporous silica nanoparticles (MSNPs)... Any type of silica material finds specific applications and needs specific physical characterization!
There is a direct correlation between the physical properties of the powder on the one hand and the performance of the process and the properties of the final components on the other. Therefore, characterisation of the powders allows for process optimisation and improves the finished product.
Characterization of the API solid state is key to reduce possible future manufacturing or formulation issues and cut drug product development costs and time. Discover more!
Due to its high degree of microporosity, one gram of activated carbon can reach a surface area of 3,000 m2 as determined by gas adsorption. Discover more about its extraordinary properties!
Several pharmaceutical ingredients (API) tend to crystallize in different crystalline packings (polymorphs). In a pharmaceutical formulation, the identity or the possible conversion of the API polymorph could alter the characteristics and the efficacy of the pharmaceutical form, leading to a different bioavailability. In this work we show how polymorphism can be successfully recognized and characterized by using MDRS (Morphologically-Directed Raman Spectroscopy), a powerful technique that combines automated particle imaging with Raman spectroscopy to provide particle size, shape and chemical identification in a single analysis.