Pharmaceutical

Particle size distribution

Particle size distribution analysis is one of the services offered by Alfatestlab for the characterisation of powder, suspension and emulsion products. Accurate particle size distribution over a representative number of particles is a key quality parameter for a variety of products in many industries.

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Particle shape

The analysis of particle morphology is one of the services offered by Alfatestlab for the characterization of powders and liquid suspensions. In addition to particle size distribution, particle shape and agglomerates analysis deliver fundamental information for both R&D and troubleshooting of industrial processes.

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Cell rupture

In AlfatestLab we use Microfluidizer technology for effective cell lysis on any type of cells:  bacterial, mammalian, plant, insect, fungi, algae and yeast cells – while ensuring a high protein recovery. Microfluidizer® technology breaks cells with high efficiency while maintaining intracellular contents integrity and allow for easiest downstream purification.

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Biomolecular interactions

AlfatestLab uses 2 extremely versatile analytical techniques, ITC microcalorimetry and BioLayer Interferometry (BLI), to study interactions without molecular weight limits, in native conditions, label-free and in real time, in the mM-nM field.

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EVs characterization

Alfatestlab is equipped with the latest technology platform to provide rapid, reliable and accurate characterization of EVs and exosomes following MISEV 2018 guidelines1. Based on NTA and Exoview analysis, our services for EVs and exosomes offers multidimensional data sets enabling an advanced understanding of complex EV populations.

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High pressure homogenizer

In AlfatestLab we are equipped with a Microfluidizer, for the high-pressure homogenization of dispersions. This unique technology that ensures scale-up * allows for the reduction of particle size or emulsion droplets, the disaggregation, the encapsulation of active ingredients, the formation of SUV or liposomes from MLV, and therefore the lab-scale production of nano – stable dispersions. Contact us to process your samples in AlfatestLab, including pre and post process granulometric analysis in the service.

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Stability analysis

Liquid dispersions, suspensions and emulsions, are encountered in a wide range of industry including Food & beverage, pharmaceuticals, personal care, paint, ceramics, speciality chemicals…. Stability is a key parameter that will impact processing, performance, appearance, texture, storage condition and shelf life of the final product.

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High resolution SEM images

Alfatestlab provides scanning electron microscopy (SEM) images including elemental analysis EDX (Energy Dispersive X-ray Analysis) when required. SEM images and EDX analysis provide fundamental information with a resolution down to 10nm.

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Real density/ Skeletal Density

Alfatestlab provides real density analysis of solids, powders and slurries using helium picnometry. Density is an important physical characteristic of materials. It is defined as the relationship between the mass of an object and its volume. Density indicates the amount of a material that occupies a defined volume at a certain temperature.

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Surface area and porosimetry

Alfatestlab provides BET specific surface area, as well as pores dimensional distribution and volume analysis of solids and powders with gas physisorption techniques. Surface area and porosity are physical properties that influence the quality and behaviour of porous materials: materials with identical weight and volume but different specific surface area may differ in terms of surface activity and adsorption volume.

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