Cell rupture

In AlfatestLab we use Microfluidizer technology for effective cell lysis on any type of cells:  bacterial, mammalian, plant, insect, fungi, algae and yeast cells – while ensuring a high protein recovery. Microfluidizer® technology breaks cells with high efficiency while maintaining intracellular contents integrity and allow for easiest downstream purification.

Biomolecular interactions

AlfatestLab uses 2 extremely versatile analytical techniques, ITC microcalorimetry and BioLayer Interferometry (BLI), to study interactions without molecular weight limits, in native conditions, label-free and in real time, in the mM-nM field.

Protein quantification

The correct quantification of biomolecules is a fundamental aspect in the development, control and monitoring of any bioprocess: from screening and optimization of the best conditions of expression and purification up to the monitoring of biomolecules production on an industrial scale.

Exosomes and EVs characterization

Alfatestlab is equipped with the latest technology platform to provide rapid, reliable and accurate characterization of EVs and exosomes following MISEV 2018 guidelines1. Based on NTA and Exoview analysis, our services for EVs and exosomes offers multidimensional data sets enabling an advanced understanding of complex EV populations.

Single-cell Secretome & Proteome

Alfatestlab offers a unique analytical service through the single-cell platform Isoplexis. The technology measures the “functional phenotype” of each cell, allowing for complete single-cell functional characterization.

High resolution SEM images

Alfatestlab provides scanning electron microscopy (SEM) images including elemental analysis EDX (Energy Dispersive X-ray Analysis) when required. SEM images and EDX analysis provide fundamental information with a resolution down to 10nm.